Recent Work

The overarching goal of the Gu lab is to develop novel therapy for the regeneration of heart, lung, and vasculature in patients with congenital cardiac and pulmonary defects. Towards this goal, the Gu lab conducts translational and interdisciplinary research using patient-specific induced pluripotent stem cells (iPSCs), vessel and lung organoids, animal models, single cell RNA/ATAC sequencing, and spatial transcriptomics for disease modeling and high-throughput drug screening.